On Monday, I updated my HTC One to the official 4.2.2 update over the air. I have noticed that the battery consumption is considerably faster than previously before.
It is likely that after a new update, the battery needs a few weeks to settle down, but my drainage is twice as fast as previously.
I would be curious to know if you are affected and how many apps/games you have installed? I have a total of 80 apps.